I'm on Mac OSX, so it could just be something to do with Reaper Mac Beta or something. I'm not recording anything. This is the first track I've done in Reaper, I can't comment on whether it's only this track. It seems to work if I solo the drums, and the bass separately, but playing them together is a no-no. The bass channel is clean, and the drum channel is a bus with a Reaper EQ and Reaper Compressor on it. My MacBook is the late 2008 Aluminum version (Now discontinued) and has 2Mb of RAM and a 2GHz dual-core processor. The problem only just started today when I was working on the track. Hope that clears up a few things. :D